Longer Life

Natural Compound Extends Life

In All Health Watch, Anti-Aging, Diet and Nutrition, Featured Article, Longevity by INH Research0 Comments

It’s called “cellular senescence”…and it’s shortening your life.

When a cell in the body is senescent, it can’t divide anymore. It sends out signals of inflammation, and the immune system clears it out, making way for healthy new cells.

That’s the way it goes when you’re young, anyway.

As you age, your immune response diminishes. Over time, damaged senescent cells accumulate.

This causes low-level inflammation. That’s the culprit behind the most common and serious ailments of aging, including cancer, heart disease, and Alzheimer’s.1 12

But a new study has identified a natural compound that reduces the number of senescent cells in the body, slowing aging and extending lifespan.

The research was conducted at the University of Minnesota Medical School. In a previous study, the same team had found that senolytics can improve health and extend lifespan.3

Senolytics are small molecules capable of destroying senescent cells. The scientists discovered that senolytics can improve health and lifespan when given to seniors.

With that established, the latest study was aimed at attempting to identify which senolytics are the most effective.

The researchers tested 10 flavonoids in mice to see if they were effective senolytics. Flavonoids are compounds found in fruits and vegetables. They have antioxidant and anti-inflammatory effects.

The study was the first of its kind. It had previously been impossible to determine how specific compounds would affect different types of cells.

But the scientists used a technique called mass cytometry for the first time in aging research. It allows scientists to track the activity of specific molecules.4

The flavonoid that worked best was fisetin. When given to aging mice, fisetin was most effective in reducing senescent cells. The rodents taking it had better health and lived longer.

Professor Paul D. Robbins was one of the study authors. The results “suggest that we can extend the period of health” even toward the end of life, he said.

8 Best Sources of Fisetin

To take advantage of the health benefits of fisetin, increase your intake of foods containing the age-delaying compound:

  • Strawberries
  • Apples
  • Persimmons
  • Onions
  • Grapes
  • Kiwis
  • Peaches
  • Cucumbers

Fisetin is also available in supplement form. It’s sold at health food stores and online. Formulations vary, so follow the label directions for the correct dosage.

Editor’s NoteRecent studies show that the symptoms of aging are just like any others. They can be treated or eliminated. Go here to discover specific ways you can stop the clock – and even turn it back.

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References:
1 https://www.healthline.com/health/chronic-inflammation
2 https://www.ncbi.nlm.nih.gov/pubmed/15681803
3 https://www.medicalnewstoday.com/articles/323247.php
4 https://medicalxpress.com/news/2018-10-aging.html

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