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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.Data sources include IBM Watson Micromedex updated 10 Aug 2020 Cerner Multum updated 3 Aug 2020 Wolters Kluwer updated 10 Aug 2020 andothers.
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Kranz aDomain 1: Scope and Purpose1.A subset of children in the clinical trials 1340 levofloxacin-treated and 893 non-fluoroquinolone-treated enrolled in a prospective, long-term levaquin tendon tears study to assess the levaquin tendon tears of protocol-defined musculoskeletal disorders arthralgia, arthritis, tendinopathy, gait abnormality during 60 days and 1 year following the first dose of the study drug.
Children treated with levofloxacin had a significantly higher incidence of musculoskeletal disorders when compared to the non-fluoroquinolone-treated children as illustrated in Table 7.
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