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Modafinil
Clinical data
Trade namesProvigil, Alertec, Modavigil, others
AHFS/Drugs.comMonograph
MedlinePlusa602016
License dataUS   FDA: Modafinil
Pregnancy categoryAU: B3 US: C (Risk not ruled out) [3]
Dependence liabilityPsychological: Very low [1] Physical: Negligible [1]
Addiction liabilityVery low to low [2]
Routes of administrationBy mouth (tablets) [3]
ATC codeN06BA07 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: Schedule IV
Pharmacokinetic data
BioavailabilityNot determined due to the aqueous insolubility
Protein binding62.3%
MetabolismHepatic (primarily via amide hydrolysis; [4] CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5 involved [5]
Elimination half-life15 hours ( R -enantiomer), 4 hours ( S -enantiomer) [6]
ExcretionUrine (80%)

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Modafinil properties
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Active substanceprovigil
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The criteria for narcolepsy include either: 1 recurrent daytime naps or lapses into sleep that occur almost daily for at least three months, plus sudden bilateral loss of postural muscle tone in association with intense emotion cataplexy or 2 a complaint of excessive sleepiness or sudden muscle weakness with associated features: sleep paralysis, hypnagogic hallucinations, automatic behaviors, disrupted major sleep episode; and polysomnography demonstrating one of the following: sleep latency what is the generic for modafinil than 10 minutes or what is the generic for modafinil eye movement REM sleep latency what is the generic for modafinil than 20 minutes.

For entry into these studies, all patients were required to have objectively documented excessive daytime sleepiness, via a Multiple Sleep Latency Test MSLT with two or more sleep onset REM periods and the absence of any other clinically significant active medical or psychiatric disorder.Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug Read the entire FDA prescribing information for Provigil Modafinil ead the Provigil User Reviews Provigil Patient Information is supplied by Cerner Multum, Inc.

and Provigil Consumer information is supplied by First Databank, Inc. used under license and subject to their respective copyrights. hat is Provigil and how is it used?

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Modafinil tablets are a federally controlled modalert 200 mg use C-IV because it can be abused or lead to dependence. Keep modafinil tablets in a safe place to prevent misuse and abuse.1 Department of Psychiatry, The Catholic University of Korea College of Medicine, Seoul, Republic of Korea. 2 Department of Psychiatry, Korea University, College of Medicine, Seoul, Republic of Korea.

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