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Vardenafil
Clinical data
Trade namesLevitra, Staxyn, Vivanza
AHFS/Drugs.comMonograph
MedlinePlusa603035
License dataEU  EMA:  by INN
Pregnancy categoryAU: B3 US: B (No risk in non-human studies)
Routes of administrationOral
ATC codeG04BE09 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability15%
Protein binding95%
MetabolismHepatic (CYP3A4)
Elimination half-life4–5 hours
ExcretionBiliary

Ritonavir onward prolonged the medicine-life of vardenafil to 25. readings see section 4. Co-administration of ketoconazole 200 mg a fixed CYP3A4 boner, with vardenafil 5 mg taunted in a 10-fold copycat in vardenafil AUC and a 4-fold termination in vardenafil Cmax see elf 4.

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Grapefruit juice being a weak inhibitor of CYP3A4 gut wall metabolism, may give rise to modest increases in plasma levels of vardenafil see section 4. The pharmacokinetics of vardenafil 20 mg was not affected by co-administration with the H2-antagonist ranitidine 150 mg twice daily digoxin, warfarin, glibenclamide, alcohol mean maximum blood alcohol level of 73 mg/dl or single doses of antacid magnesium hydroxide/aluminium hydroxide Although levitra de 10 mg para que sirve interaction studies were not conducted for all medicinal products, population pharmacokinetic analysis showed no levitra de 10 mg para que sirve on vardenafil pharmacokinetics of the following concomitant medicinal products: acetylsalicylic acid, ACE-inhibitors, beta-blockers, weak CYP3A4 inhibitors, diuretics and medicinal products for the treatment of diabetes sulfonylureas and metformin There are no data on the interaction of vardenafil and non-specific phosphodiesterase inhibitors such as theophylline or dipyridamole.I generally cut a 20 mg in half which works just fine.

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Vardenafil has vasodilator properties, resulting in mild and transient decreases in blood pressure see section 5. Patients with left ventricular outflow obstruction, e.PDE5 inhibitors, including LEVITRA may potentiate the hypotensive effects of GC stimulators.

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Men dealing with erectile dysfunction can erectile dysfunction. They include: Epimedium brevicornum, Zinc, Citrus Sinensis, inkgo Biloba, Tribulus Terrestris, Panax Ginseng root extract and Pomegranate: Viasil naturally helps in increasing blood flow and oxygen to the body.Vardenafil reduces the concentration of ritonavir and indinavir and may reduce the effect these drugs.

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Nd not known can not be estimated from available data Within each frequency grouping, adverse reactions are presented in order of decreasing seriousness. Penile haemorrhage, haematospermia and haematuria have been reported in clinical trials and spontaneous post-marketing data with the use of all PDE5 inhibitors, including vardenafil.219-24.

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