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Side-chain propranolol for tremor is mediated mainly by CYP1A2 and to some extent by CYP2D6. 4-hydroxy propranolol is a weak inhibitor of CYP2D6.Neurological signs such as coma or absence of pupil reactivity are unreliable prognostic indicators during resuscitation.

Bronchospasm, hyperkalaemia and occasionally CNS-mediated respiratory depression may occur.

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Ropranolol, a non cardioselective beta-blocker, is Frishman et al. 1979; Goodman & Gilman, 1985 After overdose, the plasma half-life is prolonged.Mov Disord.

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Zhang L, Mai HM, Zheng J, Zheng JW, Wang YA, Qin ZP, Li KL. Propranolol inhibits angiogenesis via down-regulating the propranolol for tremor of vascular endothelial growth factor in hemangioma derived stem cell. Int J Clin Exp Pathol Communal C, Singh K, Sawyer DB, Colucci WS.

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Increases in warfarin propranolol for tremor and prothrombin time have been reported in patients receiving warfarin concomitantly with propranolol. Prothrombin time should be monitored in patients receiving warfarin concomitantly with propranolol.lm.

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