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Following parenteral administration, the biologically inactive clindamycin phosphate is hydrolysed to clindamycin. hen the equivalent of 300mg of clindamycin is injected intramuscularly, a mean peak plasma concentration of 6 microgram/ml is achieved within three hours; 600mg gives a peak concentration of 9 microgram/ml.CPS Compendium of pharmaceuticals and specialties.
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Depending on the results, this measure can make a reduction in dosage or an increase in the dose interval of 8 or even 12 hours necessary.43rd ed.
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